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奥密克戎变异株新型冠状病毒感染5例

Five patients with novel coronavirus Omicron variant of concern infection

摘要:

目的:分析奥密克戎(Omicron)变异株新型冠状病毒(新冠病毒)感染患者的临床特征,为后续临床治疗提供实践数据和经验。方法:2021年12月18日至2022年1月28日嘉兴市第一manbet官网登录 收治了5例奥密克戎变异株新冠病毒感染患者。总结分析患者的临床资料,包括性别、年龄、住院时间、疫苗接种情况、临床症状、实验室检查指标〔白细胞计数(WBC)、淋巴细胞计数(LYM)、嗜酸粒细胞计数(EOS)、超敏C-反应蛋白(hs-CRP)、新冠病毒抗体免疫球蛋白(IgG和IgM)〕、胸部CT表现、治疗经过及疾病转归情况等。结果:5例奥密克戎变异株新冠病毒感染患者均为男性,年龄24~37岁。其中4例接种过新冠疫苗的患者(1例接种第3针加强针,3例仅接种前2针疫苗)胸部CT检查均未见感染灶;实验室检查显示WBC、LYM、EOS和hs-CRP水平均为正常,仅表现为轻度上呼吸道感染症状。1例未接种过新冠疫苗的患者胸部CT检查可见病毒性肺炎征象;实验室检查显示WBC、hs-CRP水平升高,提示细菌感染;患者发热及咳嗽、咳痰等呼吸道症状明显,且治疗时间长。5例患者均在常规西药抗病毒治疗基础上加用中药连花清瘟颗粒和白虎银翘汤,治疗效果明显。结论:接种新冠疫苗的奥密克戎变异株新冠病毒感染患者临床症状更轻,胸部CT表现不明显,患者恢复较快;中药连花清瘟颗粒和白虎银翘汤对此类患者治疗效果明显。

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abstracts:

Objective:To analyze clinical characteristics of patients with novel coronavirus Omicron variant of concern infection, and to provide practical data and experience for subsequent clinical treatment.Methods:A retrospective analysis was performed for the clinical data of 5 cases with novel coronavirus Omicron variant of concern infection treated in the First Hospital of Jiaxing from December 18, 2021 to January 28, 2022. The patients' clinical data were recorded, including gender, age, length of hospital stay, vaccination status, clinical symptoms, laboratory indicators [white blood cell count (WBC), lymphocyte count (LYM), eosinophil count (EOS), hypersensitivity C-reactive protein (hs-CRP), novel coronavirus antibody immunoglobulin (IgG and IgM)], chest CT, treatment course and disease outcome.Results:All 5 patients were male, aged 24-37 years old. Four patients were vaccinated with novel coronavirus vaccine (one patient received 3 doses of the vaccine and 3 patients received only the first 2 doses of the vaccine), and no infection was found in chest CT. Laboratory examination showed that WBC, LYM, EOS and hs-CRP levels were normal, and only showed mild symptoms of upper respiratory tract infection. One patient was not vaccinated with novel coronavirus vaccine, and signs of viral pneumonia could be seen in chest CT, laboratory examination showed that WBC and hs-CRP levels increased, suggesting that bacterial infection, fever, cough, sputum and other respiratory symptoms were obvious, and the treatment time was long. All 5 patients were treated with Chinese medicine Lotus antipyretic and Baihu Yinqiao decoction based on routine antiviral therapy.Conclusions:Patients with novel coronavirus Omicron variant of concern infection vaccinated with the novel coronavirus vaccine have milder clinical symptoms, with less obvious chest CT findings and faster recovery. Chinese medicine Lotus antipyretic and Baihu Yinqiao decoction has obvious therapeutic effect on such patients.

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作者: 刘宣言 [1] 胡巧巧 [1] 姚明 [1] 陈文宇 [1] 张齐 [1] 黄劼 [1]
期刊: 《中华危重病急救医学》2022年34卷5期 471-474页 MEDLINEISTICPKUCSCD
栏目名称: 论著·新型冠状病毒肺炎
DOI: 10.3760/cma.j.cn121430-20220118-00074
发布时间: 2024-09-03
基金项目:
浙江省教育厅一般科研项目 浙江省嘉兴市科技应急攻关项目 浙江省嘉兴市医学重点学科建设项目 General Scientific Research Project of Education Department of Zhejiang Province of China Jiaxing City Science and Technology Emergency Tackling Project of Zhejiang Province of China Jiaxing City Key Medical Discipline Project of Zhejiang Province of China
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