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Background::Multifocal motor neuropathy (MMN), Lewis-Sumner syndrome (LSS), and many chronic inflammatory demyelinating polyradiculoneuropathies (CIDPs) are representative of acquired multifocal polyneuropathy and are characterized by conduction block (CB). This retrospective study aimed to investigate the demyelinating distribution and the selective vulnerability of MMN, LSS, and CIDP with CB (CIDP-CB) in nerves.Methods::Fifteen LSS subjects (107 nerves), 24 MMN subjects (176 nerves), and 17 CIDP-CB subjects (110 nerves) were included. Their clinical information was recorded, blood and cerebrospinal fluid tests were conducted, and nerve conductions of the median, ulnar, radial, peroneal, and tibial nerves were evaluated. CB, temporal dispersion, distal motor latency (DML), and F-wave latency were recorded, and nerve conduction velocity, terminal latency index, and modified F-wave ratio were calculated.Results::CB was more likely to occur around the elbow in CIDP-CB than in MMN (78.6

作者:Zhou Xia-Jun;Zhu Ying;Zhu De-Sheng;Han Lu;Liu Qian-Yun;Liang Xiao-Niu;Hao Yong;Li Ze-Zhi;Guan Yang-Tai

来源:中华医学杂志英文版 2020 年 133卷 21期

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作者:
Zhou Xia-Jun;Zhu Ying;Zhu De-Sheng;Han Lu;Liu Qian-Yun;Liang Xiao-Niu;Hao Yong;Li Ze-Zhi;Guan Yang-Tai
来源:
中华医学杂志英文版 2020 年 133卷 21期
标签:
Multifocal motor neuropathy Lewis-Sumner syndrome Chronic inflammatory demyelinating neuropathy Conduction block Demyelination Multifocal motor neuropathy Lewis-Sumner syndrome Chronic inflammatory demyelinating neuropathy Conduction block Demyelination
Background::Multifocal motor neuropathy (MMN), Lewis-Sumner syndrome (LSS), and many chronic inflammatory demyelinating polyradiculoneuropathies (CIDPs) are representative of acquired multifocal polyneuropathy and are characterized by conduction block (CB). This retrospective study aimed to investigate the demyelinating distribution and the selective vulnerability of MMN, LSS, and CIDP with CB (CIDP-CB) in nerves.Methods::Fifteen LSS subjects (107 nerves), 24 MMN subjects (176 nerves), and 17 CIDP-CB subjects (110 nerves) were included. Their clinical information was recorded, blood and cerebrospinal fluid tests were conducted, and nerve conductions of the median, ulnar, radial, peroneal, and tibial nerves were evaluated. CB, temporal dispersion, distal motor latency (DML), and F-wave latency were recorded, and nerve conduction velocity, terminal latency index, and modified F-wave ratio were calculated.Results::CB was more likely to occur around the elbow in CIDP-CB than in MMN (78.6