Background::Little was known about the association among time in range (TIR), time above range (TAR), time below range (TBR), and cancer mortality among patients with type 2 diabetes. We aimed to investigate the association among TIR, TAR, TBR, and the risk of cancer mortality among patients with type 2 diabetes.Methods::A total of 6225 patients with type 2 diabetes were prospectively recruited in Shanghai, China. TIR was measured with continuous glucose monitoring at baseline and was defined as the average percentage of time in the target glucose range during a 24 h period. Cox proportion hazard regression analysis was used to determine the association between TIR and the risk of cancer mortality.Results::During a mean follow-up of 7.10 years, we confirmed 237 death events related to cancer. The multivariable-adjusted hazard ratio (HR) for cancer mortality was 1.32 (95

作者：Shen Yun；Wang Chunfang；Wang Yaxin；Lu Jingyi；Chen Lei；Zhang Lei；Lu Wei；Zhu Wei；Hu Gang；Xia Tian；Zhou Jian

来源：中华医学杂志英文版 2022 年 135卷 3期